Tuberculosis

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Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium tuberculosis. It mainly affects the lungs but can also spread to other organs such as the brain, kidneys, spine, and lymph nodes. Tuberculosis spreads through the air when an infected person coughs, sneezes, or speaks. :contentReference[oaicite:1]{index=1}

Tuberculosis is one of the most common infectious diseases worldwide and remains a major public health concern. :contentReference[oaicite:2]{index=2}

Overview

Tuberculosis primarily affects the respiratory system and damages lung tissues.

contentReference[oaicite:3]{index=3}

The disease may exist in two forms:

  • Latent Tuberculosis
  • Active Tuberculosis

People with latent TB do not show symptoms and cannot spread the disease, while active TB causes illness and can infect others. :contentReference[oaicite:4]{index=4}

Symptoms

Common symptoms of active tuberculosis include:

  • Persistent cough
  • Chest pain
  • Coughing blood
  • Fever
  • Night sweats
  • Fatigue
  • Weight loss
  • Loss of appetite

Symptoms usually develop gradually over time. :contentReference[oaicite:5]{index=5}

Causes

Tuberculosis is caused by Mycobacterium tuberculosis bacteria.

The disease spreads through airborne droplets released when infected individuals:

  • Cough
  • Sneeze
  • Speak
  • Spit

Crowded living conditions and weak immune systems increase the risk of transmission. :contentReference[oaicite:6]{index=6}

Types of Tuberculosis

Pulmonary Tuberculosis

Affects the lungs and is the most common form of TB.

Extrapulmonary Tuberculosis

Affects organs outside the lungs such as:

  • Brain
  • Kidneys
  • Spine
  • Lymph nodes

Latent Tuberculosis

Inactive infection without symptoms.

Multidrug-Resistant Tuberculosis

A form of TB resistant to major anti-TB medicines. :contentReference[oaicite:7]{index=7}

Diagnosis

Doctors diagnose tuberculosis using:

  • Chest X-ray
  • Sputum test
  • Tuberculin skin test
  • Blood tests
  • CT scan
  • Molecular diagnostic tests

Rapid molecular tests help identify TB and drug resistance. :contentReference[oaicite:8]{index=8}

Treatment

Tuberculosis is treated using antibiotics over several months.

Common anti-TB medicines include:

  • Isoniazid
  • Rifampicin
  • Pyrazinamide
  • Ethambutol

Treatment must be completed fully to prevent drug resistance. :contentReference[oaicite:9]{index=9}

Prevention

Tuberculosis prevention methods include:

  • BCG vaccination
  • Early diagnosis
  • Proper ventilation
  • Wearing masks
  • Completing treatment
  • Avoiding close contact with infected individuals

Complications

Untreated tuberculosis may lead to:

  • Lung damage
  • Respiratory failure
  • Meningitis
  • Organ damage
  • Death

Drug-resistant TB is more difficult to treat and requires specialized medical care. :contentReference[oaicite:10]{index=10}

Importance

Tuberculosis remains a major global health challenge despite being preventable and curable. Early diagnosis and proper treatment are essential to reduce transmission and mortality. :contentReference[oaicite:11]{index=11}

See Also